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章鱼彩票app-「肺癌攻略连载专栏」Part5.5 靶向医治

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“美国非小细胞肺癌NCCN攻略,该攻略旨在给患者供给医治信息,协助患者从“0”到“1”知道肺癌,找到合适的医治计划。本攻略有些主张或许不合适你,你的医师或许会依据你的状况和其他要素拟定不相同的医治计划。”

本大众号将非小细胞肺癌NCCN攻略重新整理拆分,将以中英文在大众号连载的办法发布,本攻略不能做任何商业用途,转载请联络本大众号。

译者:朱志华、梅伟健

Part5.5 靶向医治

靶向医治是一系列的药物。它的作业原理是中止协助癌细胞成长的要害分子。与化疗比较,它对正常细胞的危害更小。针对肺癌的靶向医治在攻略6中列出。

Targeted therapy is a class of drugs. It works by stopping key molecules that help cancer cells grow. It is less likely to harm normal cells than chemotherapy. Targeted therapies for lung cancer are listed in Guide 6.

这些疗法会在接下来描绘。这儿列出了一些副作用。请您的医治小组列出一切常见和稀有的副作用。在第7部分中,将供给关于谁应该收到这些药物的信息。靶向医治一般是在某些骤变呈现的时分进行的。

These treatments are briefly described next. Some side effects are listed. Ask your treatment team for a full list of common and rare side effects. In Part 7,information on who should receive these drugs is provided. Targeted therapy is often given when certain mutations are present.

1、EGFR骤变

细胞成长是由操控增加的信号介导的。EGFR是肺癌细胞外表受体之一,能够触发成长信号。一些患有肺癌患者有一些的基因骤变,导致EGFR过度活泼。跟着EGFR的过度活泼,新的癌细胞敏捷构成。有5种药物用于阻挠EGFRs引发成长信号。请参见图17所示。

Cell growth is started by growth signals. EGFR is one of the surface receptors in lung cancer cells that can trigger growth signals. Some people with lung cancer have gene mutations that cause EGFR to be overactive. With overactive EGFRs, new cancer cells form quickly. There are five medicines used to stop EGFRs from triggering growth signals. See Figure 17.

2、埃罗替尼

埃罗替尼与表皮成长因子受体的一部分衔接,这部分是细胞内的一个组成部分。EGFR的这一部分是酪氨酸激酶。它是磷酸盐的一个对接地,由于它从一个分子移动到另一个分子。埃罗替尼阻断磷酸盐,阻挠 EGFR完结它们的作业。因而,成长信号不是由EGFR 触发的。

Erlotinib attaches to a part of EGFR that is within cells. This part of EGFR is a tyrosine kinase. It is a docking site for phosphate as it is moved from one molecule to another. Erlotinib blocks phosphate and stops EGFRs from completing their job. Thus, growth signals aren’t triggered by EGFRs.

埃罗替尼是一种药丸。它应该是空腹服用的。剂量因人而异。你的医师会决议你需求的剂量。

Erlotinib is made as a pill. It should be taken on an empty stomach. The dose given differs among people. Your doctor will decide the dose you need.

埃罗替尼常见的副作用是皮疹、腹泻;不感到饥饿;衰弱;呼吸困难;和咳嗽。你或许有严峻的眼睛,皮肤,肺,肾,或肝脏问题,但这些是稀有的。其他一些稀有的事情包含肠水肿和流血。假如你怀孕了,想要怀孕,或许哺乳,不要服用埃罗替尼。

Common side effects of erlotinib are rash; diarrhea; not feeling hungry; weakness; trouble breathing; and cough. You may have severe eye, skin, lung, kidney, or liver problems, but these are rare. Other rare events include tears in your gut and bleeding. Don’t take erlotinib if you are pregnant, trying to get pregnant, or breastfeeding.

3、吉非替尼

吉非替尼和埃罗替尼是相同类型的药物。吉非替尼是一种药丸。它能够与食物一同服用也能够不。一般是一天运用一次。

Gefitinib is the same type of drug as erlotinib. Gefitinib is made as a pill. It can be taken with or without food. It is usually taken once a day.

吉非替尼最常见的副作用是皮肤反响和腹泻。严峻的副作用包含肠水肿和眼睛的问题。

The most common side effects of gefitinib are ski reactions and diarrhea. Serious side effects include a tear in your gut and eye problems.

很少有严峻的肺和肝问题发作。不要在怀孕、想要怀孕或哺乳的状况下服用吉非替尼。

Very rarely, severe lung and liver problems occur. Don’t take gefitinib if pregnant, trying to get pregnant, or breastfeeding.

4、阿法替尼

阿法替尼和埃罗替尼是相同类型的药物。可是,它也阻挠了另一种外表受体HER2。与埃罗替尼和吉非替尼不同,阿法替尼与EGFR和HER2不别离。它在细胞上的作用不会中止。

Afatinib is the same type of drug as erlotinib. However, it also stops another surface receptor called HER2. Unlike erlotinib and gefitinib, afatinib doesn’t detach from EGFR and HER2. Its effect on cells doesn’t stop.

阿法替尼被制造成药丸。它应该空腹服用。剂量因人而异。你的医师会决议你需求的剂量。

Afatinib is made as a pill. It should be taken on an empty stomach. The dose given differs among people. Your doctor will decide the dose you need.

阿法替尼常见的副作用包含腹泻、厌恶、吐逆、皮疹 或枯燥、痤疮、指甲感染、口腔溃疡、瘙痒、不感觉饿。腹泻和皮肤问题或许很严峻。相同,你也或许有肺、肝、心脏和眼睛的问题。假如你怀孕了,想要怀孕,或许哺乳,不要服用阿法替尼。

Common side effects of afatinib include diarrhea, nausea, vomiting, skin rash or dryness, acne, nail infection, mouth sores, itching, and not feeling hungry. Diarrhea and skin problems may be severe. Likewise, you may also have lung, liver, heart, and eye problems. Don’t take afatinib if you are pregnant, trying to get pregnant, or breastfeeding.

5、奥斯替尼

奥斯替尼和埃罗替尼是相同类型的药物。它是一种药丸。它能够与食物一同服用,也能够不。剂量因人而异。你的医师会决议你需求的剂量。

Osimertinib is the same type of drug as erlotinib. It is made as a pill.It can be taken with or without food. The dose given differs among people.Your doctor will decide the dose you need.

奥斯替尼最常见的副作用是疲惫、腹泻、皮疹、皮肤枯燥,指甲的改变。指甲的改变包含发红,肿胀,痛苦,指甲开裂和脱离。奥斯替尼也或许引起严峻的眼、肺或心脏问题,但这些问题是稀有的。假如你怀孕或哺乳,奥斯替尼或许会危害你的宝宝。

The most common side effects of osimertinib are tiredness, diarrhea, skin rash, dry skin, and nail changes. Nail changes include redness, swelling, pain, and nails breaking and detaching from the finge. Osimertinib may also cause severe eye, lung, or heart problems, but these problems are rare. Osimertinib may harm your baby if you’re pregnant or breastfeeding.

6、西妥昔单抗

西妥昔单抗衔接到细胞外的EGFR分子结尾。因而,其他分子(配体)被阻挠附着在EGFR上。

Cetuximab attaches to the ends of EGFRs that are outside of the cell. Thus, molecules (ligands) are blocked from attaching to and turning on EGFRs.

即使没有任何增加信号。西妥昔单抗也能招引免疫细胞来杀死癌细胞。

No growth signals are started. Cetuximab also attracts immune cells that help to kill the cancer cells.

当运用另一种EGFR靶向药物2癌症开展时能够考虑西 妥昔单抗与阿法替尼联合运用。它是经过打针的。一般每周或每隔一周一次。初次医治或许需求2小时。后来的医治只需求1个小时。

Cetuximab with afatinib may be received if the cancer worsens while taking another EGFR-targeted therapy. It is given by infusion. It is usually received once a week or every other week. It may take 2 hours to receive the first dose. Later doses will take only 1 hour.

西妥昔单抗常见的副作用是皮肤问题。这些问题包含痤疮样的皮疹,枯燥的皮肤,眼睛炎症,和皮肤感染。其他常见的症状是腹泻和食欲不振。血镁含量或许下降。稀有但严峻的副作用包含越狱第四季对输液的严峻反响和肺危害。假如你怀孕或哺乳,西妥昔单抗或许会危害你的宝宝。

Common side effects of cetuximab are skin problems. These problems include acne-like rash, dry skin, eye inflammation, and skin infections. Other common side effects are diarrhea and loss of appetite. Blood magnesium levels may drop. Rare but serious side effects include a severe reaction to the infusion and lung damage. Cetuximab may harm your baby if you’re pregnant or breastfeeding.

7、ALK重组

ALK是一种能够引发肺癌细胞成长信号的外表受体。在ALK重组的肺癌中,ALK是活泼的。由于过度活泼的ALK,新的癌细胞敏捷构成。有四种药物用于阻挠ALK触发成长信号。

ALK is a surface receptor that can trigger growth signals in lung cancer cells. In lung cancers with an ALK rearrangement, ALK is overactive. With overactive ALK, new cancer cells form quickly. There are four medicines used to stop ALK from triggering growth signals.

8、克唑替尼

克唑替尼衔接ALK的细胞内部分。ALK的这部分是酪氨酸激酶。它是磷酸盐的一个对接地,由于它从一个分子移动到另一个分子。克唑替尼阻断磷酸盐,阻断ALK信号。

Crizotinib attaches to a part of ALK that is within cells. This part of ALK is a tyrosine kinase. It is a docking site for phosphate as it is moved from one molecule to another. Crizotinib blocks the phosphate and stops ALK signaling.

克唑替尼制成药丸。每天两次。它能够与食物一同服用也能够不。

Crizotinib is made as a pill. It is taken twice a day. It can be taken with or without food.

克唑替尼常见的副作用包含视力问题;胃病(厌恶、吐逆、腹泻、便秘);不感到饥饿;水肿;虽然睡了,感觉很累。它会引起头晕、肺部感染和神经危害。严峻的副作用或许包含肺、肝和心脏问题。假如你在怀孕或哺乳期,它或许会危害你的宝宝。

Common side effects of crizotinib include vision problems; stomach problems (nausea, vomiting, diarrhea, constipation); not feeling hungry; fluid buildup; and feeling tired despite sleep. It can cause dizziness, lung infections, and nerve damage. Severe problems may include lung, liver, and heart problems. Crizotinib may harm your baby if you’re pregnant or breastfeeding.

9、色瑞替尼

色瑞替尼是和克唑替尼相同类型的药物。可是,他们的结构不相同。因而,当克唑替尼不能起作用时,色瑞替尼能够阻挠磷酸盐。

Ceritinib is the same type of drug as crizotinib. However, the structure of ceritinib differs from crizotinib. Thus, it is able to block phosphate when crizotinib can’t.

色瑞替尼被制成药丸。它应该是空腹服用的。可是,你的医师或许主张你吃点食物。一天一次。

Ceritinib is made as a pill. It should be taken on an empty stomach. However, your doctor may suggest a different dose with food. It is taken once a da .

色瑞替尼常见的副作用是腹泻、厌恶、吐逆、腹痛、疲惫、不感觉饿,瘦身。它很少导致严峻的肺、心脏和肝脏 问题。假如你怀孕或哺乳,色瑞替尼或许会危害你的宝宝。

Common side effects of ceritinib are diarrhea, nausea, vomiting, abdominal pain, tiredness, not feeling hungry, and weight loss. It rarely causes severe lung, heart, and liver problems. Ceritinib may harm your baby if you’re pregnant or breastfeeding.

10、阿雷替尼

阿雷替尼是与克唑替尼相同类型的药物。可是,它的结构是不相同的。因而,当克唑替尼不能起作用时,它能够阻挠磷酸盐。

Alectinib is the same type of drug as crizotinib and ceritinib. However, its structure differs.Thus, it is able to block phosphate when other medicines do not.

阿雷替尼被制成药丸。每天用食物吃两次。常见的副作用是疲惫、便秘肿胀和肌肉痛苦。它很少导致严峻的肺、心脏、肾脏和肝脏问题。假如你怀孕或哺乳的话,阿雷替尼或许会危害你的宝宝。

Alectinib is made as a pill. It is taken twice a day with food. Common side effects of alectinib are tiredness, constipation, swelling, and muscle pain. It rarely causes severe lung, heart, kidney, and liver problems. Alectinib may harm your baby if you’re pregnant or breastfeeding.

11、布格替尼

布格替尼的作用与其他药物类似,但其结构不相同。因而,当其他药物没有用时,它能够阻挠磷酸盐。布格替尼被制成药丸。它能够与食物一同服章鱼彩票app-「肺癌攻略连载专栏」Part5.5 靶向医治用,也能够不。一天一次。在医治的第一周半剂量服用。常见副作用包含厌恶、腹泻、头痛、咳嗽、和疲惫。它或许会导致严峻的肺、心脏、视力和肌肉问题。假如你怀孕或哺乳的话,它或许会危害你的宝宝。

Brigatinib works much like the other medicines but its structure differs.Thus, it is able to block phosphate when other medicines do not.Brigatinib is made as a pill. It can be taken with or without food. It is taken once a day. It is given at half dose for the first week of treatment Common side effects include nausea, diarrhea, headache, cough, and tiredness. It may cause severe lung, heart, vision, and muscle problems. Brigatinib may harm your baby if you’re pregnant or breastfeeding.

12、ROS1重组

ROS1是外表受体,能够引发肺癌细胞成长信号。在有ROS1重组的肺癌中,ROS1是过度活泼的。跟着过度活泼的ROS1,新的癌细胞敏捷构成。有两种药物用于阻挠ROS1触发成长信号。

ROS1 is surface receptor that can trigger growth signals in lung cancer cells. In lung cancers with a ROS1 rearrangement, ROS1 is overactive. With overactive ROS1, new cancer cells form quickly. There are two medicines used to stop ROS1 from triggering growth signals.

13、色瑞替尼

除了ALK,色瑞替尼也能经过ROS1中止成长信号。它的作用是阻断酪氨酸激酶的磷酸搬运。请阅览ALK重组的部分,了解更多关于色瑞替尼的信息。

Besides ALK, ceritinib also stops growth signals from ROS1. It works by blocking the transfer of phosphate by the tyrosine kinase. Read the section, ALK rearrangement, to learn more about ceritinib.

14、克唑替尼

除了ALK,克唑替尼也能经过ROS1中止成长信号。它的作用是阻断酪氨酸激酶的磷酸搬运。请阅览ALK 重组的部分,了解更多关于克唑替尼的信息。

Besides ALK, crizotinib also stops growth signals from ROS1. It works by blocking the transfer of phosphate by the tyrosine kinase. Read the section, ALK rearrangement, to learn more about crizotinib.

15、BRAF V600E骤变

BRAF是细胞内的激酶。它将磷酸盐从一个分子搬运到另一个分子。磷酸盐能激起下一个增加的信号通路。在有BRAF V600E骤变的肺癌中,BRAF过度活泼。跟章鱼彩票app-「肺癌攻略连载专栏」Part5.5 靶向医治着过度活泼的BRAF,新的癌细胞敏捷构成。有三种药物能够医治过度活泼的BRAF信号。参见图18所示。

BRAF is a kinase inside of cells. It transfers phosphates from one molecule to another. The phosphate “turns on” the next growth signal in the pathway. In lung cancers with a BRAF V600E mutation, BRAF is overactive. With overactive BRAF, new cancer cells form quickly. There are three medicines to treat overactive BRAF signals. See Figure 18.

16、达拉非尼+曲美替尼

达拉非尼和曲美替尼最常联合用于医治。达拉非尼附着在BRAF上,并阻挠磷酸盐的搬运。曲美替尼阻断了另一种叫MEK的激酶搬运磷酸盐。BRAF和MEK在相同的成长信号通路中。MEK在这条通路上将会进一步下调。

Dabrafenib and trametinib are most often used together for treatment. Dabrafenib attaches to BRAF and blocks the transfer of phosphate. Trametinib blocks the transfer of phosphate by another kinase called MEK. BRAF and MEK are within the same growth signal pathway. MEK is further down in the pathway.

达拉非尼和曲美替尼被制成药丸。两者都应该空腹服用。达拉非尼每天要服两次。曲美替尼则在每天的同一时间服用一次。

Dabrafenib and trametinib are made as pills. Both should be taken on an empty stomach. Dabrafenib is taken twice a day. Trametinib is taken once a day at the same time each day.

常见的副作用包含发烧、发冷、和疲惫。你或许会感到厌恶、吐逆、腹泻或不感到饥饿。你的皮肤会变得枯燥或起疹子。你的脸、臂膀或腿或许会肿起来。出血、咳嗽和呼吸短暂也很常见。

Common side effects of dabrafenib with trametinib include fever, chills, and fatigue. You may feel nauseated, vomit, have diarrhea, or not feel hungry. Your skin may become dry or get a rash. You face, arms, or legs may swell. Bleeding, cough, and shortness of breath are also common.

稀有但严峻的副作用包含你的肠水肿,血栓,心脏,眼睛,或许肺部的问题。发烧、皮疹或出血或许是严峻的。血糖或许会变得很高。其他类型的癌症或许会开展。

There are rare but serious side effects.These include tears in your gut, blood clots, and heart, eye, or lung problems. Fever, rash, or bleeding may be severe. Blood sugar may become very high. Other types of cancer may develop.

假如你想要一个孩子,告知你的医师。你的精子数量会下降。妇女怀孕或许会有困难。假如你怀孕或哺乳,不要运用达拉非尼和曲美替尼。这些药或许会危害你章鱼彩票app-「肺癌攻略连载专栏」Part5.5 靶向医治的孩子。

If you want to have a baby, tell your doctor. Sperm counts can drop in men. Women may have trouble getting pregnant. Don’t use dabrafenib and trametinib if you’re pregnant or breastfeeding. These medicines may harm your baby.

17、独自达拉非尼

达拉非尼和曲美替尼联用或许对你的身体危害太大。在这种状况下,仅运用达拉非尼或许是一种挑选。常见的副作用包含皮肤的改变。你的皮肤会变得很厚或长疣。你的手或脚或许会变成赤色、肿胀、剥皮或感觉柔软。其他常见的副作用包含发烧、关节痛苦和掉发。

Dabrafenib and trametinib may be too hard on your body. In this case, dabrafenib used alone may be an option. Common side effects include changes in your skin. Your skin may become thick or get warts. Your hands or feet may become red, swell, peel, or feel tender. Other common side effects are feve, joint aches, and hair loss.

18、维罗非尼

假如达拉非尼+曲美替尼不能运用,维罗非尼也或许是一个选项。它像达拉非尼相同,中止了BRAF信号。它被用来医治黑色素瘤。用于医治肺癌则需求更多的研讨。

Vemurafenib may also be an option if dabrafenib with trametinib can’t be taken. It works like dabrafenib and stops BRAF signals. It is used to treat melanoma. More research is needed on lung cancer.

维罗非尼制成药丸。每天两次。它能够与食物一同服用,也能够不。副作用关于黑素瘤和肺癌或许是类似的。

Vemurafenib is made as a pill. It is taken twice a day. It can be taken with or without food.

常见的黑色素瘤医治副作用包含关节痛苦、疲惫和厌恶。你的皮肤或许会有疹子或疣。你或许有掉发或简单被晒伤。你或许会感到痒。严峻的方面包含过敏或皮肤反响,心脏问题,肝脏或肾脏危害,和眼睛问题。

Side effects may be alike for melanoma and lung cancer. Common side effects for melanoma treatment include joint pain, tiredness, and nausea. Your skin may get a rash or warts. You may have hair loss or easily get a sunburn. You may feel itchy. Serious side effects include allergic or skin reactions, heart problems, liver or kidney damage, and eye problems.

19、VEGF 通路

癌细胞需求血液中的食物和氧气以便成长。癌细胞从成长在肿瘤中的血管中取得血液。VEGF(血管内皮成长因子)是促进血管成长的分子之一。

Cancer cells need the food and oxygen in blood to grow. Cancer cells get blood from blood vessels that have grown into the tumor. VEGF (vascular endothelial growth factor) is one of the molecules that triggers the growth of these blood vessels.

不像其他的生物标志物,VEGF不是骤变。可是,它在大多数肺癌中起作用。VEGF是由癌细胞发生的。它从癌细胞搬运到内皮细胞。内皮细胞构成血管。

Unlike other biomarkers, VEGF is not mutated. However, it plays a role in most lung cancers. VEGF is made by cancer cells. It travels from cancer cells to endothelial cells. Endothelial cells form blood vessels.

VEGF与内皮细胞外表受体相结合。VEGF与外表受体的附着会触发成长信号。有两种药物用于阻挠VEGF引起的成长信号。

VEGF attaches to surface receptors on the outside of endothelial cells. Attachment of VEGF to surface receptors triggers growth signals. There are two medicines used to stop the growth signals caused by VEGF.

20、贝伐单抗

贝伐单抗在VEGF与内皮细胞受体相连之前,现与VEGF结合。参见图19所示。因而,VEGF不能附着在受体上。VEGF没有引起成长信号。

Bevacizumab attaches to VEGF before it attaches to receptors on endothelial cells. See Figure 19. As a result, VEGF can’t attach to receptors. No growth signals caused by VEGF are started.

贝伐单抗是由输液完结的。初次医治大约需求90分钟,之后大约需求30分钟。贝伐单抗一般会与化疗一同进行,4 - 6次医治后则能够独自运用,以坚持杰出的作用。依据化疗计划的不同,每2或3周给予一次。

Bevacizumab is given by infusion. It takes about 90 minutes to get the first dose and 30 minutes for later doses. Bevacizumab is always first given with chemotherapy and after 4 to 6 treatments, may be given alone to maintain good results. It is given every 2 or 3 weeks depending on the chemotherapy.

常见副作用是高血压,流鼻血,头痛。你也或许有流鼻涕、尿蛋白和直肠出血。稀有但严峻的副作用包含中风、心脏病、血凝块、肾脏危害、肠道内的裂口、身体部位的反常通道和出血。很少会呈现脑危害。假如你怀孕了,试着怀孕,或许哺乳,不要服用贝伐珠单抗。

Common side effects of bevacizumab are high blood pressure, nosebleeds, and headache. You might also have a runny nose, protein in the urine, and rectal bleeding. Rare but serious side effects include stroke, heart attack, blood clots, kidney damage, a tear in your gut, abnormal passage between body parts, and bleeding. Very rarely, brain damage occurs. Don’t take bevacizumab if you are pregnant, trying to get pregnant, or breastfeeding.

21、雷莫芦单抗

雷莫芦单抗与VEGF受体在细胞外结合。这阻挠了VEGF的附着。VEGF没有引起成长信号。

Ramucirumab attaches to VEGF receptors on the outside of endothelial cells. This blocks VEGF from attaching. No growth signals caused by VEGF are started.

雷莫芦单抗由输液完结。需求60分钟才干得到悉数剂量。它总是与化疗一同进行。每两周进行一次化疗。

Ramucirumab is given by infusion. It takes 60 minutes to receive the full dose. Ramucirumab is always given with chemotherapy. It is given every two weeks on the first day of chemotherap .

常见的副作用是高血压和腹泻。严峻的方面包含出血、血块、内脏的水肿、身体部位的反常通道和缓慢的创伤愈合。很少会呈现脑危害。假如怀孕,测验怀孕,或哺乳不要服用它。

Common side effects of ramucirumab are high blood pressure and diarrhea. Serious side effects include bleeding, blood clots, tears in your gut, abnormal passage between body parts, and slow wound healing. Very rarely, brain damage occurs. Don’t take bevacizumab if pregnant, trying to get pregnant, or breastfeeding.

22、其他靶向分子

虽然稀有,还有其他生物符号的肺癌的医治。这些医治办法被同意用于肺癌或其他癌症,但仍需求更多的研讨。这种医治办法包含针对HER2的ado -曲妥珠单抗。Cabozantinib和vandetanib针对RET。除了针对ALK和ROS1,克唑替尼也能针对MET。

Although rare, there are other biomarkers of lung cancer for which there are treatments. These treatments are approved for lung or other cancers but still need more research. Such treatments include ado-trastuzumab for HER2. Cabozantinib and vandetanib target RET. In addition to targeting ALK and ROS1, crizotinib targets MET.

23、弥补和代替医学

CAM (弥补和代替疗法)是一组医师很少给予的医治。现在与很多人重视CAM对癌症的医治。现在正在研讨许多CAMs,看它们是否真的有用。

CAM (complementary and alternative medicine) is a group of treatments that aren’t often given by doctors. There is much interest today in CAM for cancer. Many CAMs are being studied to see if they are truly helpful.

辅佐药物是与常见的医学医治一同给予的医治。虽然CAMs不能杀死癌细胞,但它们能够改进你的舒适和健康。两个比如是针灸医治痛苦和瑜伽放松。

Complementary medicines are treatments given along with usual medical treatments. While CAMs aren’t known to kill cancer cells, they may improve your comfort and wellbeing. Two examples are acupuncture for pain management and yoga for relaxation.

代替医学用来代替常见的医学医治。一些代替药物被出售用于医治,虽然它们尚未被证明在 临床试验中有用。假如有充沛的依据证明 CAMs或其他医治办法治好了癌症,他们将会被归入这本书中。

Alternative medicine is used in place of usual medicine. Some alternative medicines are sold as cures even though they haven’t been proven to work in clinical trials. If there was good proof that CAMs or other treatments cured cancer, they would be included in this book.

假如你正在运用CAMs,告知你的医治团队是很重要的。他们能够告知你哪些CAMs或许是有用的,哪些CAMs或许会约束药物医治的作用。

It is important to tell your treatment team if you are using any CAMs. They can tell you which CAMs may be helpful and which CAMs may limit how well medical treatments work.

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